Posts

Showing posts with the label Peptide Synthesis

Pegylated Peptide Sequences help Reduce Hydrophobic Peptide Aggreagtion.

  Genosphere Biotechnologies specializes in the production of hydrophobic peptide sequences and long peptides by carefuly planning the synthesis routes and incorporating many processes to overcome difficulties in the manufacturing process. While we have good reputation for being able to produce difficult peptides, it is always best to avoid known areas of concern when possible. For example, an overly hydrophobic peptide sequence, even when we are able to be produced it, generally cause production delays, increased manufacturing costs and difficulty in future scale up. Our expert peptide chemists specialize in sequence design that optimizes stability, solubility, and manufacturability of scale up, while maintaining the core active region of the peptide unchanged.   While the below tips are meant to help solubility, stability and future scale up, we understand changing a peptides amino acid composition isn’t always possible. In these cases, our expert peptide chemists will opt...

The Chemical basis of Peptide Synthesis

Image
  Peptides are essential in a large variety of biological processes involving all organisms.   Peptides show a diversity of biochemical activities. They can act as hormones, antibiotics, enzyme modulators, and receptors. A number of peptides have been shown to play a key role in specific disease states such as Alzheimer’s disease, cardiovascular disease, and diabetes. Well studied and synthetically produced peptides include insulin, oxytocin, vasopressin and endorphins. Peptide Synthesis Companies Genosphere Biotechnologies synthesize custom peptides for research and development laboratories since 1996.   Among peptide synthesis companies Genosphere Biotechnologies is one of the most trusted group of peptide chemists in the industry and is your ideal partner for the custom synthesis of peptides and complex organic molecules.   Genosphere Biotechnologies offers a full range of technologies.   We produce research grade peptides from simple peptides to the mos...